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・ Trimethylamine-oxide aldolase
・ Trimethylaminuria
・ Trimethylarsine
・ Trimethylarsine (data page)
・ Trimethylbenzenes
・ Trimethylborane
・ Trimethyldiborane
・ Trimethyldiphenylpropylamine
・ Trimethylene carbonate
・ Trimethylenemethane
・ Trimethylenemethane cycloaddition
・ Trimethylgallium
・ Trimethylglycine
・ Trimethylhexamethylenediamine
・ Trimethylindium
Trimethyllysine dioxygenase
・ Trimethylolethane
・ Trimethylolethane trinitrate
・ Trimethylolpropane
・ Trimethylolpropane phosphite
・ Trimethyloxonium tetrafluoroborate
・ Trimethylpentane
・ Trimethylphosphine
・ Trimethylsilane
・ Trimethylsilanol
・ Trimethylsilyl
・ Trimethylsilyl azide
・ Trimethylsilyl chloride
・ Trimethylsilyl cyanide
・ Trimethylsilyl cyclopentadiene


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Trimethyllysine dioxygenase : ウィキペディア英語版
Trimethyllysine dioxygenase

In enzymology, a trimethyllysine dioxygenase () is an enzyme that catalyzes the chemical reaction
:N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 \rightleftharpoons 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2
The 3 substrates of this enzyme are N6,N6,N6-trimethyl-L-lysine, 2-oxoglutarate, and O2, whereas its 3 products are 3-hydroxy-N6,N6,N6-trimethyl-L-lysine, succinate, and CO2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor. The systematic name of this enzyme class is N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating). Other names in common use include trimethyllysine alpha-ketoglutarate dioxygenase, TML-alpha-ketoglutarate dioxygenase, TML hydroxylase, 6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase, and (3-hydroxylating). This enzyme participates in lysine degradation and L-carnitine biosynthesis. It has 3 cofactors: iron, Ascorbate, and Fe2+.
==See also==

*Carnitine biosynthesis
*γ-Butyrobetaine hydroxylase
*4-''N''-Trimethylaminobutyraldehyde dehydrogenase

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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